Interaction between replication protein A and p53 is disrupted after UV damage in a DNA repair-dependent manner

Replication protein A (RPA) is required for both DNA replication and nucleotide excision repair. Previous studies have shown that RPA interacts with the tumor suppressor p53. Herein, we have mapped a 20-amino acid region in the N-terminal part of p53 that is essential for its binding to RPA. This re...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Abramova, Natalia A., Russell, Jackie, Botchan, Michael, Li, Rong
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1997
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23787/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9207066/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.14.7186
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