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The basic domain of Rev from human immunodeficiency virus type 1 specifically blocks the entry of U4/U6.U5 small nuclear ribonucleoprotein in spliceosome assembly.

Human immunodeficiency virus type 1 (HIV-1) encodes a regulatory protein, Rev, which is required for cytoplasmic expression of incompletely spliced viral mRNA. Rev binds to a cis-acting Rev-responsive element (RRE) located within the env region of HIV-1. It has previously been shown that a 17-amino-...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kjems, J, Sharp, P A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237863/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8331728/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.8.4769-4776.1993
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