Association of U2, U4, U5, and U6 small nuclear ribonucleoproteins in a spliceosome-type complex in absence of precursor RNA.

Small nuclear ribonucleoprotein particles (snRNPs) associate to form multi-snRNP complexes during splicing of mRNA precursors. A vast majority of the three snRNPs U4, U5, and U6 are present in a nuclear extract in a single complex, while U1 and U2 snRNPs exist as separate particles. Under conditions...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Konarska, M M, Sharp, P A
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1988
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281776/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2969592/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.15.5459
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