Physicochemical dissociation of CD4-mediated syncytium formation and shedding of human immunodeficiency virus type 1 gp120.

The mechanism of CD4-mediated fusion via activated human immunodeficiency virus type 1 (HIV-1) gp41 and the biological significance of soluble CD4 (sCD4)-induced shedding of gp120 are poorly understood. The purpose of these investigations was to determine whether shedding of gp120 led to fusion acti...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Fu, Y K, Hart, T K, Jonak, Z L, Bugelski, P J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237746/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8510207/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.7.3818-3825.1993
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