Inhibition of human immunodeficiency virus syncytium formation and virus replication by castanospermine.

Castanospermine (1,6,7,8-tetrahydroxyoctahydroindolizine) is a plant alkaloid that modifies glycosylation by inhibiting alpha-glucosidase I. Castanospermine is shown to inhibit syncytium formation induced by the envelope glycoprotein of the human immunodeficiency virus and to inhibit viral replicati...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Walker, B D, Kowalski, M, Goh, W C, Kozarsky, K, Krieger, M, Rosen, C, Rohrschneider, L, Haseltine, W A, Sodroski, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1987
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Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299490/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2825177/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.22.8120
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