Inhibition of human immunodeficiency virus syncytium formation and virus replication by castanospermine.

Castanospermine (1,6,7,8-tetrahydroxyoctahydroindolizine) is a plant alkaloid that modifies glycosylation by inhibiting alpha-glucosidase I. Castanospermine is shown to inhibit syncytium formation induced by the envelope glycoprotein of the human immunodeficiency virus and to inhibit viral replicati...

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Autores principales: Walker, B D, Kowalski, M, Goh, W C, Kozarsky, K, Krieger, M, Rosen, C, Rohrschneider, L, Haseltine, W A, Sodroski, J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1987
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC299490/
https://ncbi.nlm.nih.gov/pubmed/2825177
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