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Apolipoprotein A-I and its amphipathic helix peptide analogues inhibit human immunodeficiency virus-induced syncytium formation.

The envelope (membrane) glycoprotein of HIV is essential for virus attachment and entry into host cells. Additionally, when expressed on the plasma membrane of infected cells, the envelope protein is responsible for mediating cell-cell fusion which leads to the formation of multinucleated giant cell...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Principais autores: Owens, B J, Anantharamaiah, G M, Kahlon, J B, Srinivas, R V, Compans, R W, Segrest, J P
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1990
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296843/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2170446/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114819
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