Specificity of the STAT4 Genetic Association for Severe Disease Manifestations of Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a genetically complex disease with heterogeneous clinical manifestations. A polymorphism in the STAT4 gene has recently been established as a risk factor for SLE, but the relationship with specific SLE subphenotypes has not been studied. We studied 137 SNPs in t...

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Main Authors: Taylor, Kimberly E., Remmers, Elaine F., Lee, Annette T., Ortmann, Ward A., Plenge, Robert M., Tian, Chao, Chung, Sharon A., Nititham, Joanne, Hom, Geoffrey, Kao, Amy H., Demirci, F. Yesim, Kamboh, M. Ilyas, Petri, Michelle, Manzi, Susan, Kastner, Daniel L., Seldin, Michael F., Gregersen, Peter K., Behrens, Timothy W., Criswell, Lindsey A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2008
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377340/
https://ncbi.nlm.nih.gov/pubmed/18516230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000084
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