Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus

The TNFAIP3 (tumor necrosis factor alpha–induced protein 3) gene encodes a ubiquitin editing enzyme, A20, that restricts NF-κB–dependent signaling and prevents inflammation. We show that three independent SNPs in the TNFAIP3 region (rs13192841, rs2230926 and rs6922466) are associated with systemic l...

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Bibliografiske detaljer
Main Authors: Musone, Stacy L, Taylor, Kimberly E, Lu, Timothy T, Nititham, Joanne, Ferreira, Ricardo C, Ortmann, Ward, Shifrin, Nataliya, Petri, Michelle A, Kamboh, M Ilyas, Manzi, Susan, Seldin, Michael F, Gregersen, Peter K, Behrens, Timothy W, Ma, Averil, Kwok, Pui-Yan, Criswell, Lindsey A
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897246/
https://ncbi.nlm.nih.gov/pubmed/19165919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.202
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