Specificity of the STAT4 Genetic Association for Severe Disease Manifestations of Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a genetically complex disease with heterogeneous clinical manifestations. A polymorphism in the STAT4 gene has recently been established as a risk factor for SLE, but the relationship with specific SLE subphenotypes has not been studied. We studied 137 SNPs in t...

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Autori principali: Taylor, Kimberly E., Remmers, Elaine F., Lee, Annette T., Ortmann, Ward A., Plenge, Robert M., Tian, Chao, Chung, Sharon A., Nititham, Joanne, Hom, Geoffrey, Kao, Amy H., Demirci, F. Yesim, Kamboh, M. Ilyas, Petri, Michelle, Manzi, Susan, Kastner, Daniel L., Seldin, Michael F., Gregersen, Peter K., Behrens, Timothy W., Criswell, Lindsey A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377340/
https://ncbi.nlm.nih.gov/pubmed/18516230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000084
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