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The herpes simplex virus type 1 reactivation function lies outside the latency-associated transcript open reading frame ORF-2.

The latency-associated transcription unit has been shown to be important for in vivo reactivation of herpes simplex virus from the latent state. A recombinant virus was constructed to alter the largest open reading frame in this region. This virus had a wild-type reactivation phenotype, suggesting t...

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Dettagli Bibliografici
Autori principali: Farrell, M J, Hill, J M, Margolis, T P, Stevens, J G, Wagner, E K, Feldman, L T
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1993
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC237719/
https://ncbi.nlm.nih.gov/pubmed/8388517
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