The herpes simplex virus type 1 reactivation function lies outside the latency-associated transcript open reading frame ORF-2.

The latency-associated transcription unit has been shown to be important for in vivo reactivation of herpes simplex virus from the latent state. A recombinant virus was constructed to alter the largest open reading frame in this region. This virus had a wild-type reactivation phenotype, suggesting t...

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Dettagli Bibliografici

Pubblicato in:	J Virol
Autori principali:	Farrell, M J, Hill, J M, Margolis, T P, Stevens, J G, Wagner, E K, Feldman, L T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237719/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8388517/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.6.3653-3655.1993
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