DNA damage and cell cycle arrest induced by 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F 203, NSC 703786) is attenuated in aryl hydrocarbon receptor deficient MCF-7 cells

The fluorinated benzothiazole analogue 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F 203, NSC 703786) is a novel agent with potent and selective antitumour properties and, in the form of its L-lysylamide prodrug Phortress (NSC 710305), is a current candidate for early phase clinical studies....

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Bibliografiske detaljer
Main Authors: Trapani, V, Patel, V, Leong, C-O, Ciolino, H P, Yeh, G C, Hose, C, Trepel, J B, Stevens, M F G, Sausville, E A, Loaiza-Pérez, A I
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2003
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377159/
https://ncbi.nlm.nih.gov/pubmed/12592376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600722
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