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Transforming variants of the avian myc-containing retrovirus FH3 arise prior to phenotypic selection.

The avian retrovirus FH3, which encodes a Gag-Myc fusion protein, transforms chicken macrophages but not fibroblasts. However, passage of FH3 viral stock in fibroblasts leads to emergence of a virus capable of fibroblast transformation. This virus has not acquired myc mutations; instead, it carries...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Tikhonenko, A T, Linial, M L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237715/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8497071/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.6.3635-3638.1993
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