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Avian proto-myc genes promoted by defective or nondefective retroviruses are single-hit transforming genes in primary cells.

Lymphomas of certain strains of chickens infected by retroviruses frequently contain recombinant transforming genes in which the promoter of the cellular proto-myc gene is replaced by that of a defective rather than an intact retrovirus. Here we ask whether the resulting hybrid genes are sufficient...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Zhou, R P, Duesberg, P H
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1989
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298142/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2554285/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.20.7721
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