Transforming variants of the avian myc-containing retrovirus FH3 arise prior to phenotypic selection.
The avian retrovirus FH3, which encodes a Gag-Myc fusion protein, transforms chicken macrophages but not fibroblasts. However, passage of FH3 viral stock in fibroblasts leads to emergence of a virus capable of fibroblast transformation. This virus has not acquired myc mutations; instead, it carries...
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| Udgivet i: | J Virol |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1993
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237715/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8497071/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.6.3635-3638.1993 |
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