Tumour dose response to the antivascular agent ZD6126 assessed by magnetic resonance imaging

ZD6126 is a vascular targeting agent that disrupts the tubulin cytoskeleton of proliferating neo-endothelial cells. This leads to the selective destruction and congestion of tumour blood vessels in experimental tumours, resulting in extensive haemorrhagic necrosis. In this study, the dose-dependent...

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Autores principales: Robinson, S P, McIntyre, D J O, Checkley, D, Tessier, J J, Howe, F A, Griffiths, J R, Ashton, S E, Ryan, A J, Blakey, D C, Waterton, J C
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2003
Materias:
Experimental Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377119/
https://ncbi.nlm.nih.gov/pubmed/12771928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600926
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