Single Dose of the Antivascular Agent, ZD6126 (N-Acetylcolchinol-O-Phosphate), Reduces Perfusion for at Least 96 Hours in the GH3 Prolactinoma Rat Tumor Model

Tumor vasculature is an attractive therapeutic target as it differs structurally from normal vasculature, and the destruction of a single vessel can lead to the death of many tumor cells. The effects of antivascular drugs are frequently short term, with regrowth beginning less than 24 hours posttrea...

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Detalhes bibliográficos
Main Authors: McIntyre, Dominick J O, Robinson, Simon P, Howe, Franklyn A, Griffiths, John R, Ryan, Anderson J, Blakey, David C, Peers, Ian S, Waterton, John C
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502085/
https://ncbi.nlm.nih.gov/pubmed/15140404
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