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Tumour dose response to the antivascular agent ZD6126 assessed by magnetic resonance imaging
ZD6126 is a vascular targeting agent that disrupts the tubulin cytoskeleton of proliferating neo-endothelial cells. This leads to the selective destruction and congestion of tumour blood vessels in experimental tumours, resulting in extensive haemorrhagic necrosis. In this study, the dose-dependent...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2377119/ https://ncbi.nlm.nih.gov/pubmed/12771928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600926 |
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