Single Dose of the Antivascular Agent, ZD6126 (N-Acetylcolchinol-O-Phosphate), Reduces Perfusion for at Least 96 Hours in the GH3 Prolactinoma Rat Tumor Model

Tumor vasculature is an attractive therapeutic target as it differs structurally from normal vasculature, and the destruction of a single vessel can lead to the death of many tumor cells. The effects of antivascular drugs are frequently short term, with regrowth beginning less than 24 hours posttrea...

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Bibliografische gegevens
Hoofdauteurs: McIntyre, Dominick J O, Robinson, Simon P, Howe, Franklyn A, Griffiths, John R, Ryan, Anderson J, Blakey, David C, Peers, Ian S, Waterton, John C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Neoplasia Press Inc. 2004
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502085/
https://ncbi.nlm.nih.gov/pubmed/15140404
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