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Sequence Similarity Network Reveals Common Ancestry of Multidomain Proteins

We address the problem of homology identification in complex multidomain families with varied domain architectures. The challenge is to distinguish sequence pairs that share common ancestry from pairs that share an inserted domain but are otherwise unrelated. This distinction is essential for accura...

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書誌詳細
主要な著者: Song, Nan, Joseph, Jacob M., Davis, George B., Durand, Dannie
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377100/
https://ncbi.nlm.nih.gov/pubmed/18475320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000063
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