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Requirements for selection of conventional and innate T lymphocyte lineages

Mice deficient in the Tec kinase Itk develop a large population of CD8 cells with properties resembling NKT and other innate T cell lineages, including expression of memory markers, rapid production of cytokines and dependence on IL-15. Like NKT cells, these CD8 cells can be selected on hematopoieti...

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Detalhes bibliográficos
Main Authors: Horai, Reiko, Mueller, Kristen L., Handon, Robin A., Cannons, Jennifer L., Anderson, Stacie M., Kirby, Martha R., Schwartzberg, Pamela L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377064/
https://ncbi.nlm.nih.gov/pubmed/18031697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.09.012
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