Immunohistochemical analysis of p53 in vulval intraepithelial neoplasia and vulval squamous cell carcinoma

Human papillomavirus (HPV) is thought to cause some vulval squamous cell carcinomas (VSCC) by degrading p53 product. Evidence on whether HPV-negative VSCC results from p53 mutation is conflicting. We performed immunohistochemistry for p53 product on 52 cases of lone vulval intraepithelial neoplasia...

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Bibliographic Details
Main Authors: Rosenthal, A N, Hopster, D, Ryan, A, Jacobs, I J
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2003
Subjects:
Molecular and Cellular Pathology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377040/
https://ncbi.nlm.nih.gov/pubmed/12610510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600677
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