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Immunohistochemical analysis of p53 in vulval intraepithelial neoplasia and vulval squamous cell carcinoma

Human papillomavirus (HPV) is thought to cause some vulval squamous cell carcinomas (VSCC) by degrading p53 product. Evidence on whether HPV-negative VSCC results from p53 mutation is conflicting. We performed immunohistochemistry for p53 product on 52 cases of lone vulval intraepithelial neoplasia...

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Detalhes bibliográficos
Main Authors: Rosenthal, A N, Hopster, D, Ryan, A, Jacobs, I J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377040/
https://ncbi.nlm.nih.gov/pubmed/12610510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600677
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