Llwytho...

Increased expression of the ubiquitin – proteasome pathway in murine myotubes by proteolysis-inducing factor (PIF) is associated with activation of the transcription factor NF-κB

Proteolysis-inducing factor (PIF), isolated from a cachexia-inducing murine tumour, has been shown to stimulate protein breakdown in C(2)C(12) myotubes. The effect was attenuated by the specific proteasome inhibitor lactacystin and there was an elevation of proteasome ‘chymotrypsin-like’ enzyme acti...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Whitehouse, A S, Tisdale, M J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376944/
https://ncbi.nlm.nih.gov/pubmed/12966435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601132
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