Activation of ATP-ubiquitin-dependent proteolysis in skeletal muscle in vivo and murine myoblasts in vitro by a proteolysis-inducing factor (PIF)

Loss of skeletal muscle is a major factor in the poor survival of patients with cancer cachexia. This study examines the mechanism of catabolism of skeletal muscle by a tumour product, proteolysis-inducing factor (PIF). Intravenous administration of PIF to normal mice produced a rapid decrease in bo...

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Detalhes bibliográficos
Main Authors: Lorite, M J, Smith, H J, Arnold, J A, Morris, A, Thompson, M G, Tisdale, M J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364050/
https://ncbi.nlm.nih.gov/pubmed/11461093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1879
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