Induction of apoptosis in experimental human B cell lymphomas by conditional TRAIL-expressing T cells

In the present study, we demonstrate the utility of a non-tumour-forming T-cell line for the inducible gene transfer of tumour necrosis factor (TNF)-related apoptosis-inducing ligand (Apo2L/TRAIL), which has been shown to selectively induce apoptosis in malignant but not in normal cells. To generate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ucur, E, Mattern, J, Wenger, T, Okouoyo, S, Schroth, A, Debatin, K-M, Herr, I
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2003
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376862/
https://ncbi.nlm.nih.gov/pubmed/14647152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601407
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