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Incidence, mechanism and prognostic value of activated AKT in pancreas cancer
When activated, the serine/threonine kinase AKT mediates an antiapoptotic signal implicated in chemoresistance of various cancers. The mechanism(s) of AKT activation are unknown, though overexpression of HER-2/neu has been implicated in breast cancer. Therefore, we determined the incidence of activa...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2376856/ https://ncbi.nlm.nih.gov/pubmed/14647146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601396 |
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