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A Matrix Metalloproteinase-9 Activation Cascade by Hepatic Stellate Cells in Trans-differentiation in the Three-dimensional Extracellular Matrix

Hepatic stellate cells (HSCs) undergo myofibroblastic trans-differentiation in liver fibrogenesis. We previously showed that dual stimulation with three-dimensional type-I collagen and interleukin-1 (IL-1) synergistically induces HSC trans-differentiation in a manner dependent on the activation of m...

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Detalhes bibliográficos
Main Authors: Han, Yuan-Ping, Yan, Chunli, Zhou, Ling, Qin, Lan, Tsukamoto, Hidekazu
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376818/
https://ncbi.nlm.nih.gov/pubmed/17322299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M700554200
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