Overexpression, purification, crystallization and preliminary X-ray analysis of Rv2780 from Mycobacterium tuberculosis H37Rv

Rv2780, an alanine dehydrogenase from Mycobacterium tuberculosis (MtAlaDH), catalyzes the NAD-dependent interconversion of alanine and pyruvate. Alanine dehydrogenase is released into the culture medium in substantial amounts by virulent strains of mycobacteria and is not found in the vaccine strain...

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Bibliographic Details
Main Authors: Tripathi, Sarvind Mani, Ramachandran, Ravishankar
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2008
Subjects:
Crystallization Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376397/
https://ncbi.nlm.nih.gov/pubmed/18453703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108007653
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