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Overexpression, purification, crystallization and preliminary X-ray analysis of Rv2780 from Mycobacterium tuberculosis H37Rv

Rv2780, an alanine dehydrogenase from Mycobacterium tuberculosis (MtAlaDH), catalyzes the NAD-dependent interconversion of alanine and pyruvate. Alanine dehydrogenase is released into the culture medium in substantial amounts by virulent strains of mycobacteria and is not found in the vaccine strain...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tripathi, Sarvind Mani, Ramachandran, Ravishankar
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376397/
https://ncbi.nlm.nih.gov/pubmed/18453703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108007653
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