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Effector Proteins Exert an Important Influence on the Signaling-active State of the Small GTPase Cdc42

GTP-binding (G) proteins regulate the flow of information in cellular signaling pathways by alternating between a GTP-bound “active” state and a GDP-bound “inactive” state. Cdc42, a member of the Rho family of Ras-related small G-proteins, plays key roles in the regulation of cell shape, motility, a...

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Bibliographische Detailangaben
Hauptverfasser: Phillips, Matthew J., Calero, Guillermo, Chan, Britton, Ramachandran, Sekar, Cerione, Richard A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376242/
https://ncbi.nlm.nih.gov/pubmed/18348980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M706271200
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