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cAMP Inhibits Cell Migration by Interfering with Rac-induced Lamellipodium Formation

Cell migration is critical for animal development and physiological as well as pathological responses. One important step during cell migration is the formation of lamellipodia at the leading edge of migrating cells. Here we report that the second messenger cAMP inhibits the migration of mouse embry...

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Hlavní autoři: Chen, Lin, Zhang, J. Jillian, Huang, Xin-Yun
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376213/
https://ncbi.nlm.nih.gov/pubmed/18353776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800555200
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