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Elevated c-Src is linked to altered cell–matrix adhesion rather than proliferation in KM12C human colorectal cancer cells

Elevated expression and/or activity of c-Src, the prototype of the Src family of protein tyrosine kinases, is associated with the development of human colon cancer. However, despite the known pleiotropic effects of these kinases in promoting (a) cell growth downstream of growth factor receptors, and...

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Detalhes bibliográficos
Main Authors: Jones, R J, Avizienyte, E, Wyke, A W, Owens, D W, Brunton, V G, Frame, M C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376185/
https://ncbi.nlm.nih.gov/pubmed/12402152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600594
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