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c-Src inactivation reduces renal epithelial cell-matrix adhesion, proliferation, and cyst formation
c-Src is a non-receptor tyrosine kinase whose activity is induced by phosphorylation at Y418 and translocation from the cytoplasm to the cell membrane. Increased activity of c-Src has been associated with cell proliferation, matrix adhesion, motility, and apoptosis in tumors. Immunohistochemistry su...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3154563/ https://ncbi.nlm.nih.gov/pubmed/21508333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00163.2010 |
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