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Precise missense and silent point mutations are fixed in the genomes of poliovirus mutants from persistently infected cells.

Poliovirus mutants selected in persistently infected human neuroblastoma cells have a modified cell tropism and can establish a secondary persistent infection in nonneural cells, such as HEp-2c cells. Nucleotide sequence analysis revealed that the genome of a persistent mutant, S11, differed from th...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Borzakian, S, Pelletier, I, Calvez, V, Colbere-Garapin, F
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237618/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8386281/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.5.2914-2917.1993
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