Precise missense and silent point mutations are fixed in the genomes of poliovirus mutants from persistently infected cells.
Poliovirus mutants selected in persistently infected human neuroblastoma cells have a modified cell tropism and can establish a secondary persistent infection in nonneural cells, such as HEp-2c cells. Nucleotide sequence analysis revealed that the genome of a persistent mutant, S11, differed from th...
Gespeichert in:
| Veröffentlicht in: | J Virol |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
1993
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237618/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8386281/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.5.2914-2917.1993 |
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