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Precise missense and silent point mutations are fixed in the genomes of poliovirus mutants from persistently infected cells.

Poliovirus mutants selected in persistently infected human neuroblastoma cells have a modified cell tropism and can establish a secondary persistent infection in nonneural cells, such as HEp-2c cells. Nucleotide sequence analysis revealed that the genome of a persistent mutant, S11, differed from th...

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Bibliografske podrobnosti
Main Authors: Borzakian, S, Pelletier, I, Calvez, V, Colbere-Garapin, F
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC237618/
https://ncbi.nlm.nih.gov/pubmed/8386281
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