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Longitudinal variation in O(6)-alkylguanine DNA-alkyltransferase activity in the human colon and rectum
In a systematic study of O(6)-alkylguanine DNA-alkyltransferase activity in the human colon and rectum, tumours were found to occur in regions of low activity. These results are consistent with the hypothesis that O(6)-alkylguanine DNA-alkyltransferase levels and alkylating agent exposure may be imp...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2376118/ https://ncbi.nlm.nih.gov/pubmed/12107837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600455 |
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