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Centrosomal abnormalities, multipolar mitoses, and chromosomal instability in head and neck tumours with dysfunctional telomeres

Carcinomas of the head and neck typically exhibit complex chromosome aberrations but the underlying mutational mechanisms remain obscure. Evaluation of cell division dynamics in low-passage cell lines from three benign and five malignant head and neck tumours revealed a strong positive correlation b...

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Библиографические подробности
Главные авторы: Gisselsson, D, Jonson, T, Yu, C, Martins, C, Mandahl, N, Wiegant, J, Jin, Y, Mertens, F, Jin, C
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2002
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376110/
https://ncbi.nlm.nih.gov/pubmed/12107843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600438
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