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Altered Centrosome Structure Is Associated with Abnormal Mitoses in Human Breast Tumors

Centrosomes are the major microtubule organizing center in mammalian cells and establish the spindle poles during mitosis. Centrosome defects have been implicated in disease and tumor progression and have been associated with nullizygosity of the p53 tumor suppressor gene. In the present ultrastruct...

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Autori principali: Lingle, Wilma L., Salisbury, Jeffrey L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866918/
https://ncbi.nlm.nih.gov/pubmed/10595924
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