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IFNγ enhances IL-23 production during Francisella infection of human monocytes

We previously demonstrated that monocytes produce IL-23 during Francisella infection, and that IL-23 induces IFNγ from NK cells. Here, we demonstrate that IFNγ-priming of monocytes enhances IL-23 production during Francisella infection. This effect was seen on the IL12/23 p40 subunit. Induction of I...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Butchar, Jonathan P., Parsa, Kishore V. L., Marsh, Clay B., Tridandapani, Susheela
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376054/
https://ncbi.nlm.nih.gov/pubmed/18319062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2008.02.058
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