The influence of in vitro fitness defects on pneumococcal ability to colonize and to cause invasive disease

BACKGROUND: Streptococcus pneumoniae is a genetically diverse major human pathogen, yet a common colonizer of the nasopharynx. Here we analyzed the influence of defects affecting in vitro growth rate, on the ability of S. pneumoniae to colonize and to cause invasive disease in vivo. RESULTS: Of elev...

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Main Authors: Fernebro, Jenny, Blomberg, Christel, Morfeldt, Eva, Wolf-Watz, Hans, Normark, Staffan, Normark, Birgitta Henriques
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375889/
https://ncbi.nlm.nih.gov/pubmed/18423011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-8-65
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