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Emergence of Hypervirulent Mutants Resistant to Early Clearance During Systemic Serotype 1 Pneumococcal Infection in Mice and Humans
Background. Streptococcus pneumoniae serotype 1 has a high likelihood of causing invasive disease. Serotype 1 isolates belonging to CC228 are associated with low mortality, while CC217 isolates exhibit high mortality in patients. Methods. Clinical pneumococcal isolates and mutants were evaluated in...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4054898/ https://ncbi.nlm.nih.gov/pubmed/24443543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu038 |
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