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Sortase-mediated assembly and surface topology of adhesive pneumococcal pili

The rlrA genetic islet encodes an extracellular pilus in the Gram-positive pathogen Streptococcus pneumoniae. Of the three genes for structural subunits, rrgB encodes the major pilin, while rrgA and rrgC encode ancillary pilin subunits decorating the pilus shaft and tip. Deletion of all three pilus-...

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Autores principales: Fälker, Stefan, Nelson, Aaron L, Morfeldt, Eva, Jonas, Kristina, Hultenby, Kjell, Ries, Johannes, Melefors, Öjar, Normark, Staffan, Henriques-Normark, Birgitta
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680257/
https://ncbi.nlm.nih.gov/pubmed/18761697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06396.x
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