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Decreased proliferation of human melanoma cell lines caused by antisense RNA against translation factor eIF-4A1

Control of translation initiation was recognised as a critical checkpoint for cell proliferation and tumorigenesis. In human melanoma cells, we have previously reported consistent overexpression of translation initiation factor eIF-4A1. Here, we investigated by transfection of antisense constructs i...

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Detalhes bibliográficos
Main Authors: Eberle, J, Fecker, L F, Bittner, J-U, Orfanos, C E, Geilen, C C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375438/
https://ncbi.nlm.nih.gov/pubmed/12085193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600351
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