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The bisphosphonate zoledronic acid impairs membrane localisation and induces cytochrome c release in breast cancer cells

Bisphosphonates are well established in the management of cancer-induced bone disease. Recent studies have indicated that these compounds have direct inhibitory effects on cultured human breast cancer cells. Nitrogen-containing bisphosphonates including zoledronic acid have been shown to induce apop...

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Detalhes bibliográficos
Main Authors: Senaratne, S G, Mansi, J L, Colston, K W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375368/
https://ncbi.nlm.nih.gov/pubmed/11986784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600297
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