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Bones, breasts, and bisphosphonates: rationale for the use of zoledronic acid in advanced and early breast cancer
Bisphosphonates inhibit osteoclast-mediated bone resorption, thereby inhibiting the release of growth factors necessary to promote cancer cell growth, differentiation, and tumor formation in bone. These agents have demonstrated efficacy for delaying the onset and reducing the incidence of skeletal-r...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2011
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3846369/ https://ncbi.nlm.nih.gov/pubmed/24367171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BCTT.S16774 |
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