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Defective γ-aminobutyric acid type B receptor-activated inwardly rectifying K(+ )currents in cerebellar granule cells isolated from weaver and Girk2 null mutant mice

Stimulation of inhibitory neurotransmitter receptors, such as γ-aminobutyric acid type B (GABA(B)) receptors, activates G protein-gated inwardly rectifying K(+) channels (GIRK) which, in turn, influence membrane excitability. Seizure activity has been reported in a Girk2 null mutant mouse lacking GI...

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Detalhes bibliográficos
Main Authors: Slesinger, Paul A., Stoffel, Markus, Jan, Yuh Nung, Jan, Lily Y.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23753/
https://ncbi.nlm.nih.gov/pubmed/9342388
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