E7 proteins from oncogenic human papillomavirus types transactivate p73: role in cervical intraepithelial neoplasia

In common with other E2F1 responsive genes such as p14(ARF) and B-myb, the promoter of p73 is shown to be positively regulated in cell lines and primary human keratinocytes by E7 proteins from oncogenic human papillomavirus (HPV) types 16, 18, 31 and 33, but not HPV 6. Mutational analysis revealed t...

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Autors principals: Brooks, L A, Sullivan, A, O'Nions, J, Bell, A, Dunne, B, Tidy, J A, Evans, D J, Osin, P, Vousden, K H, Gusterson, B, Farrell, P J, Storey, A, Gasco, M, Sakai, T, Crook, T
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2002
Matèries:
Molecular and Cellular Pathology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375198/
https://ncbi.nlm.nih.gov/pubmed/11870517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600033
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